Statistical Approach to Decreasing the Error Rate of Noninvasive Prenatal Aneuploid Detection caused by Maternal Copy Number Variation

Analyses of cell-free fetal DNA (cff-DNA) from maternal plasma using massively parallel sequencing enable the noninvasive detection of feto-placental chromosome aneuploidy; this technique has been widely used in clinics worldwide. Noninvasive prenatal tests (NIPT) based on cff-DNA have achieved very...

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Bibliographic Details
Main Authors: Zhang, Han, Zhao, Yang-Yu, Song, Jing, Zhu, Qi-Ying, Yang, Hua, Zheng, Mei-Ling, Xuan, Zhao-Ling, Wei, Yuan, Chen, Yang, Yuan, Peng-Bo, Yu, Yang, Li, Da-Wei, Liang, Jun-Bin, Fan, Ling, Chen, Chong-Jian, Qiao, Jie
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632076/