The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins

The GemC1 coiled-coil structure has subtle differences compared with its homologues Geminin and Idas. Co-expression experiments in cells and biophysical stability analysis of the Geminin-family coiled coils suggest that the GemC1 coiled coil alone is unstable.

Bibliographic Details
Main Authors: Caillat, Christophe, Fish, Alexander, Pefani, Dafni-Eleftheria, Taraviras, Stavros, Lygerou, Zoi, Perrakis, Anastassis
Format: Online
Language:English
Published: International Union of Crystallography 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631479/