Bacterial calpains and the evolution of the calpain (C2) family of peptidases
Homologues of calpain, often thought to be an essential, cytoplasmic, calcium-dependent cysteine endopeptidase found exclusively in eukaryotes, have been found in bacterial proteomes. The homologues lack calcium-binding sites, have differing domain architectures, and can be secreted or membrane-asso...
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631099/ |