NFAT isoforms play distinct roles in TNFα-induced retinal leukostasis

The objective of this study was to determine the role of individual NFAT isoforms in TNFα-induced retinal leukostasis. To this end, human retinal microvascular endothelial cells (HRMEC) transfected with siRNA targeting individual NFAT isoforms were treated with TNFα, and qRT-PCR was used to examine...

Full description

Bibliographic Details
Main Authors: Bretz, Colin A., Savage, Sara R., Capozzi, Megan E., Suarez, Sandra, Penn, John S.
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630625/