Mechanism of bombesin-induced tonic contraction of the porcine lower esophageal sphincter

Gastroesophageal reflux disease (GERD) is a disorder that is related to an incompetent lower esophageal sphincter (LES). Previous studies showed that bombesin could increase LES pressure in humans and opossums. The aim of the present study was to characterize the effects of bombesin on porcine LES c...

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Bibliographic Details
Main Authors: Tsai, Ching-Chung, Chang, Li-Ching, Lin, Kai-Jen, Tey, Shu-Leei, Su, Yu-Tsun, Liu, Ching-Wen, Tsai, Tong-Rong, Huang, Shih-Che
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629149/