Solid lipid nanoparticles for nose to brain delivery of haloperidol: in vitro drug release and pharmacokinetics evaluation
In the present study, haloperidol (HP)-loaded solid lipid nanoparticles (SLNs) were prepared to enhance the uptake of HP to brain via intranasal (i.n.) delivery. SLNs were prepared by a modified emulsification–diffusion technique and evaluated for particle size, zeta potential, drug entrapment effic...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Elsevier
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629108/ |