Spontaneous Thrombosis and Subsequent Recanalization of a Developmental Venous Anomaly

Developmental venous anomalies (DVA) are among the most common congenital malformations of the cerebral angioarchitecture. Spontaneous thrombosis of this entity is rare, and our review of the literature found only 31 reported cases of symptomatic spontaneous thrombosis of developmental venous anomal...

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Main Authors:	Patel, Vishal J, Lall, Rishi R, Desai, Sohum, Mohanty, Aaron
Format:	Online
Language:	English
Published:	Cureus 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627833/

id	pubmed-4627833
recordtype	oai_dc
spelling	pubmed-46278332015-11-05 Spontaneous Thrombosis and Subsequent Recanalization of a Developmental Venous Anomaly Patel, Vishal J Lall, Rishi R Desai, Sohum Mohanty, Aaron Neurosurgery Developmental venous anomalies (DVA) are among the most common congenital malformations of the cerebral angioarchitecture. Spontaneous thrombosis of this entity is rare, and our review of the literature found only 31 reported cases of symptomatic spontaneous thrombosis of developmental venous anomalies. Here, we report a unique case describing the spontaneous thrombosis of a DVA leading to venous infarction and subsequent recanalization. The patient was a previously healthy 21-year-old male who presented with an acute onset of partial seizures. Following negative hypercoagulability studies and along with CT (computed tomography) and MR (magnetic resonance) imaging, the patient was treated with anticoagulant therapy and demonstrated complete functional recovery. Knowledge from our literature review of similar cases combined with the experience gained from this patient’s treatment leads us to suggest that spontaneous DVA thrombosis and venous infarction generally has a good outcome despite initially devastating neurologic deficits. Additionally, the rarity of spontaneous DVA thromboses lends itself to the need to identify possible predisposing risk factors, chief amongst these being hypercoagulopathies. Cureus 2015-09-28 /pmc/articles/PMC4627833/ /pubmed/26543692 http://dx.doi.org/10.7759/cureus.334 Text en Copyright © 2015, Patel et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Patel, Vishal J Lall, Rishi R Desai, Sohum Mohanty, Aaron
spellingShingle	Patel, Vishal J Lall, Rishi R Desai, Sohum Mohanty, Aaron Spontaneous Thrombosis and Subsequent Recanalization of a Developmental Venous Anomaly
author_facet	Patel, Vishal J Lall, Rishi R Desai, Sohum Mohanty, Aaron
author_sort	Patel, Vishal J
title	Spontaneous Thrombosis and Subsequent Recanalization of a Developmental Venous Anomaly
title_short	Spontaneous Thrombosis and Subsequent Recanalization of a Developmental Venous Anomaly
title_full	Spontaneous Thrombosis and Subsequent Recanalization of a Developmental Venous Anomaly
title_fullStr	Spontaneous Thrombosis and Subsequent Recanalization of a Developmental Venous Anomaly
title_full_unstemmed	Spontaneous Thrombosis and Subsequent Recanalization of a Developmental Venous Anomaly
title_sort	spontaneous thrombosis and subsequent recanalization of a developmental venous anomaly
description	Developmental venous anomalies (DVA) are among the most common congenital malformations of the cerebral angioarchitecture. Spontaneous thrombosis of this entity is rare, and our review of the literature found only 31 reported cases of symptomatic spontaneous thrombosis of developmental venous anomalies. Here, we report a unique case describing the spontaneous thrombosis of a DVA leading to venous infarction and subsequent recanalization. The patient was a previously healthy 21-year-old male who presented with an acute onset of partial seizures. Following negative hypercoagulability studies and along with CT (computed tomography) and MR (magnetic resonance) imaging, the patient was treated with anticoagulant therapy and demonstrated complete functional recovery. Knowledge from our literature review of similar cases combined with the experience gained from this patient’s treatment leads us to suggest that spontaneous DVA thrombosis and venous infarction generally has a good outcome despite initially devastating neurologic deficits. Additionally, the rarity of spontaneous DVA thromboses lends itself to the need to identify possible predisposing risk factors, chief amongst these being hypercoagulopathies.
publisher	Cureus
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627833/
_version_	1613495515436023808

Spontaneous Thrombosis and Subsequent Recanalization of a Developmental Venous Anomaly

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