Synthesis and Biological Evaluation of Novel Gigantol Derivatives as Potential Agents in Prevention of Diabetic Cataract

As a continuation of our efforts directed towards the development of natural anti-diabetic cataract agents, gigantol was isolated from Herba dendrobii and was found to inhibit both aldose reductase (AR) and inducible nitric oxide synthase (iNOS) activity, which play a significant role in the develop...

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Bibliographic Details
Main Authors: Wu, Jie, Lu, Chuanjun, Li, Xue, Fang, Hua, Wan, Wencheng, Yang, Qiaohong, Sun, Xiaosheng, Wang, Meiling, Hu, Xiaohong, Chen, C.-Y. Oliver, Wei, Xiaoyong
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627826/