Fatal Toxoplasma gondii infection in the giant panda

Fatal Toxoplasma gondii infection in the giant panda

Toxoplasma gondii can infect nearly all warm-blooded animals. We report an acute fatal T. gondii infection in the endangered giant panda (Ailuropoda melanoleuca) in a zoo in China, characterized by acute gastroenteritis and respiratory symptoms. T. gondii infection was confirmed by immunological an...

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Main Authors: Ma, Hongyu, Wang, Zedong, Wang, Chengdong, Li, Caiwu, Wei, Feng, Liu, Quan
Format: Online
Language:English
Published: EDP Sciences 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626621/
id pubmed-4626621
recordtype oai_dc
spelling pubmed-46266212015-11-24 Fatal Toxoplasma gondii infection in the giant panda Ma, Hongyu Wang, Zedong Wang, Chengdong Li, Caiwu Wei, Feng Liu, Quan Short Note Toxoplasma gondii can infect nearly all warm-blooded animals. We report an acute fatal T. gondii infection in the endangered giant panda (Ailuropoda melanoleuca) in a zoo in China, characterized by acute gastroenteritis and respiratory symptoms. T. gondii infection was confirmed by immunological and molecular methods. Multilocus nested PCR-RFLP revealed clonal type I at the SAG1 and c29-2 loci, clonal type II at the SAG2, BTUB, GRA6, c22-8, and L358 loci, and clonal type III at the alternative SAG2 and SAG3 loci, thus, a potential new genotype of T. gondii in the giant panda. Other possible pathogens were not detected. To our knowledge, this is the first report of clinical toxoplasmosis in a giant panda. EDP Sciences 2015 2015-10-29 /pmc/articles/PMC4626621/ /pubmed/26514595 http://dx.doi.org/10.1051/parasite/2015030 Text en © H. Ma et al., published by EDP Sciences, 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Ma, Hongyu
Wang, Zedong
Wang, Chengdong
Li, Caiwu
Wei, Feng
Liu, Quan
spellingShingle Ma, Hongyu
Wang, Zedong
Wang, Chengdong
Li, Caiwu
Wei, Feng
Liu, Quan
Fatal Toxoplasma gondii infection in the giant panda
author_facet Ma, Hongyu
Wang, Zedong
Wang, Chengdong
Li, Caiwu
Wei, Feng
Liu, Quan
author_sort Ma, Hongyu
title Fatal Toxoplasma gondii infection in the giant panda
title_short Fatal Toxoplasma gondii infection in the giant panda
title_full Fatal Toxoplasma gondii infection in the giant panda
title_fullStr Fatal Toxoplasma gondii infection in the giant panda
title_full_unstemmed Fatal Toxoplasma gondii infection in the giant panda
title_sort fatal toxoplasma gondii infection in the giant panda
description Toxoplasma gondii can infect nearly all warm-blooded animals. We report an acute fatal T. gondii infection in the endangered giant panda (Ailuropoda melanoleuca) in a zoo in China, characterized by acute gastroenteritis and respiratory symptoms. T. gondii infection was confirmed by immunological and molecular methods. Multilocus nested PCR-RFLP revealed clonal type I at the SAG1 and c29-2 loci, clonal type II at the SAG2, BTUB, GRA6, c22-8, and L358 loci, and clonal type III at the alternative SAG2 and SAG3 loci, thus, a potential new genotype of T. gondii in the giant panda. Other possible pathogens were not detected. To our knowledge, this is the first report of clinical toxoplasmosis in a giant panda.
publisher EDP Sciences
publishDate 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626621/
_version_ 1613494997740421120

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