Hypericin-mediated photodynamic therapy induces apoptosis in K562 human leukemia cells through JNK pathway modulation

Hypericin (Hyp) is traditionally used as an antidepressant and antiviral agent. It selectively accumulates in spheroids and is also used as a photosensitizer in the photodynamic therapy of cancer. The present study aimed to investigate the cytotoxic effect of Hyp-mediated photodynamic therapy (Hyp-P...

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Bibliographic Details
Main Authors: XU, YIXIAO, WANG, DEXUAN, ZHUANG, ZHIZHI, JIN, KEKE, ZHENG, LVZHEN, YANG, QING, GUO, KUNYUAN
Format: Online
Language:English
Published: D.A. Spandidos 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626167/