The prion protein constitutively controls neuronal store-operated Ca2+ entry through Fyn kinase

The prion protein constitutively controls neuronal store-operated Ca2+ entry through Fyn kinase

The prion protein (PrPC) is a cell surface glycoprotein mainly expressed in neurons, whose misfolded isoforms generate the prion responsible for incurable neurodegenerative disorders. Whereas PrPC involvement in prion propagation is well established, PrPC physiological function is still enigmatic de...

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Bibliographic Details
Main Authors: De Mario, Agnese, Castellani, Angela, Peggion, Caterina, Massimino, Maria Lina, Lim, Dmitry, Hill, Andrew F., Sorgato, M. Catia, Bertoli, Alessandro
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623396/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623396/

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