Differential post-transcriptional regulation of IL-10 by TLR2 and TLR4-activated macrophages

Differential post-transcriptional regulation of IL-10 by TLR2 and TLR4-activated macrophages

The activation of TLRs by microbial molecules triggers intracellular-signaling cascades and the expression of cytokines such as IL-10. Il10 expression is tightly controlled to ensure effective immune responses, while preventing pathology. Maximal TLR-induction of Il10 transcription in macrophages re...

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Bibliographic Details
Main Authors: Teixeira-Coelho, Maria, Guedes, Joana, Ferreirinha, Pedro, Howes, Ashleigh, Pedrosa, Jorge, Rodrigues, Fernando, Lai, Wi S, Blackshear, Perry J, O'Garra, Anne, Castro, António G, Saraiva, Margarida
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623319/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623319/

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