Axonal protection by short-term hyperglycemia with involvement of autophagy in TNF-induced optic nerve degeneration

Previous reports showed that short-term hyperglycemia protects optic nerve axons in a rat experimental hypertensive glaucoma model. In this study, we investigated whether short-term hyperglycemia prevents tumor necrosis factor (TNF)-induced optic nerve degeneration in rats and examined the role of a...

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Bibliographic Details
Main Authors: Sase, Kana, Kitaoka, Yasushi, Munemasa, Yasunari, Kojima, Kaori, Takagi, Hitoshi
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623211/