Molecular control of irreversible bistability during trypanosome developmental commitment

Phosphoproteomic and functional analysis of the developmental progression of Trypanosomes demonstrates that this transition shows bistability, with commitment to differentiation requiring new protein synthesis, and that the protein kinase NRK is a key regulator.

Bibliographic Details
Main Authors: Domingo-Sananes, Maria Rosa, Szöőr, Balazs, Ferguson, Michael A.J., Urbaniak, Michael D., Matthews, Keith R.
Format: Online
Language:English
Published: The Rockefeller University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621835/