Molecular control of irreversible bistability during trypanosome developmental commitment
Phosphoproteomic and functional analysis of the developmental progression of Trypanosomes demonstrates that this transition shows bistability, with commitment to differentiation requiring new protein synthesis, and that the protein kinase NRK is a key regulator.
Main Authors: | , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621835/ |