Association between pre-miR-27a functional polymorphism and risk of colorectal cancer in north Chinese Han population

MicroRNA-27a (miR-27a) is deemed as an oncogene in malignancies including colorectal cancer (CRC), and rs895819 within pre-miR-27a may affect its secondary structure, leading to its aberrant expression and dysfunction of its targeted gene. We investigated genotype and allele frequencies of the locus...

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Bibliographic Details
Main Authors: Bian, Quan, Chen, Jian-Jun, Gu, Jun-Ping, Xu, Jing
Format: Online
Language:English
Published: Dove Medical Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621200/