Iatrogenic CJD due to pituitary-derived growth hormone with genetically determined incubation times of up to 40 years

Iatrogenic CJD due to pituitary-derived growth hormone with genetically determined incubation times of up to 40 years

Cases of iatrogenic CJD still occur in the UK 30 years after administration of human pituitary-derived growth hormone ceased. Rudge et al. report a change over time in genotype profile at polymorphic codon 129 of the human prion protein gene in UK patients, distinct from that seen in other countries...

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Bibliographic Details
Main Authors: Rudge, Peter, Jaunmuktane, Zane, Adlard, Peter, Bjurstrom, Nina, Caine, Diana, Lowe, Jessica, Norsworthy, Penny, Hummerich, Holger, Druyeh, Ron, Wadsworth, Jonathan D. F., Brandner, Sebastian, Hyare, Harpreet, Mead, Simon, Collinge, John
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620512/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620512/

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