Pre T-Cell Receptor Alpha (pTα) Expression Patterns and Functional Analysis in Human T-Cell Lymphoblastic Leukemia

Background: The pTα/preTCR regulates the β-selection, a crucial T-cell developmental checkpoint, providing a most potent survival advantage to thymocytes mediated by the src-kinase p56Lck.

Bibliographic Details
Main Authors: Ivanyi, Philipp, Morgan, Michael, Piao, Wenji, Ukena, Sya N., Steube, Klaus, Ganser, Arnold, Franzke, Anke
Format: Online
Language:English
Published: IOS Press 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619105/