Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine

Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine

Schistosomes, parasites that cause the disease schistosomiasis in humans, are blood flukes that infect an estimated 200 million people in 76 countries. Control of schistosomiasis is currently based on repeated doses of the drug praziquantel (PZQ). Parasites showing reduced susceptibility to PZQ have...

Full description

Bibliographic Details
Main Authors: Taylor, Alexander B., Pica-Mattoccia, Livia, Polcaro, Chiara M., Donati, Enrica, Cao, Xiaohang, Basso, Annalisa, Guidi, Alessandra, Rugel, Anastasia R., Holloway, Stephen P., Anderson, Timothy J. C., Hart, P. John, Cioli, Donato, LoVerde, Philip T.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618941/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618941/

Similar Items