A Fast, Sensitive and Accurate High Resolution Melting (HRM) Technology-Based Assay to Screen for Common K-ras Mutations

A Fast, Sensitive and Accurate High Resolution Melting (HRM) Technology-Based Assay to Screen for Common K-ras Mutations

Background: Increasing evidence points to a negative correlation between K-ras mutations and patient’s response to, or survival benefit after, treatment with EGFR-inhibitors. Therefore, rapid and reliable assays for mutational analysis of the K-ras gene are strongly needed.

Bibliographic Details
Main Authors: Kramer, D., Thunnissen, F. B., Gallegos-Ruiz, M. I., Smit, E. F., Postmus, P. E., Meijer, C. J. L. M., Snijders, P.J.F., Heideman, D. A. M.
Format: Online
Language:English
Published: IOS Press 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618824/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618824/

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