Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein

Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein

Frontotemporal dementia (FTD) is a frequent form of early-onset dementia and can be caused by mutations in MAPT encoding the microtubule-associated protein TAU. Because of limited availability of neural cells from patients’ brains, the underlying mechanisms of neurodegeneration in FTD are poorly und...

Full description

Bibliographic Details
Main Authors: Ehrlich, Marc, Hallmann, Anna-Lena, Reinhardt, Peter, Araúzo-Bravo, Marcos J., Korr, Sabrina, Röpke, Albrecht, Psathaki, Olympia E., Ehling, Petra, Meuth, Sven G., Oblak, Adrian L., Murrell, Jill R., Ghetti, Bernardino, Zaehres, Holm, Schöler, Hans R., Sterneckert, Jared, Kuhlmann, Tanja, Hargus, Gunnar
Format: Online
Language:English
Published: Elsevier 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618448/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618448/

Similar Items