Antigen Gene Transfer to Human Plasmacytoid Dendritic Cells Using Recombinant Adenovirus and Vaccinia Virus Vectors

Recombinant adenoviruses (RAd) and recombinant vaccinia viruses (RVV) expressing tumour-associated antigens (TAA) are used as anti-tumour vaccines. It is important that these vaccines deliver the TAA to dendritic cells (DC) for the induction of a strong immune response. Infection of myeloid DC (MDC)...

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Bibliographic Details
Main Authors: Bontkes, Hetty J., Ruizendaal, Janneke J., Schreurs, Marco W. J., Kramer, Duco, Meijer, Chris J. L. M., Hooijberg, Erik
Format: Online
Language:English
Published: IOS Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617564/