Adiposity significantly modifies genetic risk for dyslipidemia[S]

Recent genome-wide association studies have identified multiple loci robustly associated with plasma lipids, which also contribute to extreme lipid phenotypes. However, these common genetic variants explain <12% of variation in lipid traits. Adiposity is also an important determinant of plasma li...

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Bibliographic Details
Main Authors: Cole, Christopher B., Nikpay, Majid, Lau, Paulina, Stewart, Alexandre F. R., Davies, Robert W., Wells, George A., Dent, Robert, McPherson, Ruth
Format: Online
Language:English
Published: The American Society for Biochemistry and Molecular Biology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617143/