Protective effects of tumor necrosis factor-α blockade by adalimumab on articular cartilage and subchondral bone in a rat model of osteoarthritis

We aimed to investigate the effects of an anti-tumor necrosis factor-α antibody (ATNF) on cartilage and subchondral bone in a rat model of osteoarthritis. Twenty-four rats were randomly divided into three groups: sham-operated group (n=8); anterior cruciate ligament transection (ACLT)+normal saline...

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Bibliographic Details
Main Authors: Ma, C.H., Lv, Q., Yu, Y.X., Zhang, Y., Kong, D., Niu, K.R., Yi, C.Q.
Format: Online
Language:English
Published: Associação Brasileira de Divulgação Científica 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617111/