Lysine-specific demethylase 1 mediates epidermal growth factor signaling to promote cell migration in ovarian cancer cells

Lysine-specific demethylase 1 mediates epidermal growth factor signaling to promote cell migration in ovarian cancer cells

Epigenetic abnormalities play a vital role in the progression of ovarian cancer. Lysine-specific demethylase 1 (LSD1/KDM1A) acts as an epigenetic regulator and is overexpressed in ovarian tumors. However, the upstream regulator of LSD1 expression in this cancer remains elusive. Here, we show that ep...

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Bibliographic Details
Main Authors: Shao, Genbao, Wang, Jie, Li, Yuanxia, Liu, Xiuwen, Xie, Xiaodong, Wan, Xiaolei, Yan, Meina, Jin, Jie, Lin, Qiong, Zhu, Haitao, Zhang, Liuping, Gong, Aihua, Shao, Qixiang, Wu, Chaoyang
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614681/

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