Neuromodulation accompanying focused ultrasound-induced blood-brain barrier opening

Burst-mode focused ultrasound (FUS) induces microbubble cavitation in the vasculature and temporarily disrupts the blood-brain barrier (BBB) to enable therapeutic agent delivery. However, it remains unclear whether FUS-induced BBB opening is accompanied by neuromodulation. Here we characterized the...

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Bibliographic Details
Main Authors: Chu, Po-Chun, Liu, Hao-Li, Lai, Hsin-Yi, Lin, Chung-Yin, Tsai, Hong-Chieh, Pei, Yu-Cheng
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614673/