A Novel Function of TET2 in CNS: Sustaining Neuronal Survival

DNA dioxygenases Ten-Eleven Translocation (TET) proteins can catalyze the conversion of 5-methylcytosine (5mC) of DNA to 5-hydroxymethylcytosine (5hmC), and thereby alter the epigenetic state of DNA. The TET family includes TET1, TET2 and TET3 members in mammals. Recently, accumulative research unco...

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Bibliographic Details
Main Authors: Mi, Yajing, Gao, Xingchun, Dai, Jinxiang, Ma, Yue, Xu, Lixian, Jin, Weilin
Format: Online
Language:English
Published: MDPI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613284/