Effect of Hepatitis C Virus Genotype 1b Core and NS5A Mutations on Response to Peginterferon Plus Ribavirin Combination Therapy

We examined whether hepatitis C virus (HCV) genotype 1b core- and NS5A-region mutations are associated with response to peginterferon α-2b plus ribavirin combination therapy. A total of 103 patients with high HCV genotype 1b viral loads (≥100 KIU/mL) were treated with the combination therapy. Pretre...

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Bibliographic Details
Main Authors: Nakamoto, Shingo, Imazeki, Fumio, Arai, Makoto, Yasui, Shin, Nakamura, Masato, Haga, Yuki, Sasaki, Reina, Kanda, Tatsuo, Shirasawa, Hiroshi, Yokosuka, Osamu
Format: Online
Language:English
Published: MDPI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613248/