PRP4K is a HER2-regulated modifier of taxane sensitivity
The taxanes are used alone or in combination with anthracyclines or platinum drugs to treat breast and ovarian cancer, respectively. Taxanes target microtubules in cancer cells and modifiers of taxane sensitivity have been identified in vitro, including drug efflux and mitotic checkpoint proteins. H...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Taylor & Francis
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612451/ |