The zinc sensing receptor, ZnR/GPR39, controls proliferation and differentiation of colonocytes and thereby tight junction formation in the colon
The intestinal epithelium is a renewable tissue that requires precise balance between proliferation and differentiation, an essential process for the formation of a tightly sealed barrier. Zinc deficiency impairs the integrity of the intestinal epithelial barrier and is associated with ulcerative an...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611734/ |