DNA Copy Number Changes at 8q11–24 in Metastasized Colorectal Cancer
Background: C-Myc, a well-known oncogene located on 8q24.12–q24.23, is often amplified and over-expressed in both primary and metastasizing colorectal cancer. In addition, PRL-3 (also known as PTP4A3), a tyrosine phosphatase located on 8q24.3, is amplified in colorectal cancer metastasis. Beside PR...
| Main Authors: | , , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
IOS Press
2005
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611113/ |