Enhanced Trapping of HIV-1 by Human Cervicovaginal Mucus Is Associated with Lactobacillus crispatus-Dominant Microbiota

Enhanced Trapping of HIV-1 by Human Cervicovaginal Mucus Is Associated with Lactobacillus crispatus-Dominant Microbiota

Cervicovaginal mucus (CVM) can provide a barrier that precludes HIV and other sexually transmitted virions from reaching target cells in the vaginal epithelium, thereby preventing or reducing infections. However, the barrier properties of CVM differ from woman to woman, and the causes of these varia...

Full description

Bibliographic Details
Main Authors:	Nunn, Kenetta L., Wang, Ying-Ying, Harit, Dimple, Humphrys, Michael S., Ma, Bing, Cone, Richard, Ravel, Jacques, Lai, Samuel K.
Format:	Online
Language:	English
Published:	American Society of Microbiology 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611035/

Similar Items

IgG in cervicovaginal mucus traps HSV and prevents vaginal Herpes infections
by: Wang, Ying-Ying, et al.
Published: (2014)

Diffusion of Immunoglobulin G in Shed Vaginal Epithelial Cells and in Cell-Free Regions of Human Cervicovaginal Mucus
by: Wang, Ying-Ying, et al.
Published: (2016)

Unique Insights in the Cervicovaginal Lactobacillus iners and L. crispatus Proteomes and Their Associations with Microbiota Dysbiosis
by: Borgdorff, Hanneke, et al.
Published: (2016)

Pretreatment of Human Cervicovaginal Mucus with Pluronic F127 Enhances Nanoparticle Penetration without Compromising Mucus Barrier Properties to Herpes Simplex Virus
by: Ensign, Laura M., et al.
Published: (2014)

Modeling of Virion Collisions in Cervicovaginal Mucus Reveals Limits on Agglutination as the Protective Mechanism of Secretory Immunoglobulin A
by: Chen, Alex, et al.
Published: (2015)

Draft Genome Sequence of Lactobacillus crispatus 2029
by: Karlyshev, Andrey V., et al.
Published: (2014)

Lactobacillus crispatus inhibits growth of Gardnerella vaginalis and Neisseria gonorrhoeae on a porcine vaginal mucosa model
by: Breshears, Laura M., et al.
Published: (2015)

Human cervicovaginal mucus contains an activity that hinders HIV-1 movement
by: Shukair, Shetha A., et al.
Published: (2012)

Lactobacillus crispatus Dominant Vaginal Microbiome Is Associated with Inhibitory Activity of Female Genital Tract Secretions against Escherichia coli
by: Ghartey, Jeny P., et al.
Published: (2014)

Lactobacillus Adhesion to Mucus
by: Tassell, Maxwell L. Van, et al.
Published: (2011)

Consistent Condom Use Increases the Colonization of Lactobacillus crispatus in the Vagina
by: Ma, Liyan, et al.
Published: (2013)

Cytoprotective Effect of Lactobacillus crispatus CTV-05 against Uropathogenic E. coli
by: Butler, Daniel S. C., et al.
Published: (2016)

Draft Genome Sequence of a Urinary Isolate of Lactobacillus crispatus
by: Price, Travis K., et al.
Published: (2016)

Lactobacillus crispatus inhibits the infectivity of Chlamydia trachomatis elementary bodies, in vitro study
by: Nardini, Paola, et al.
Published: (2016)

Behavioral Predictors of Colonization with Lactobacillus crispatus or Lactobacillus jensenii after Treatment for Bacterial Vaginosis: A Cohort Study
by: Mitchell, Caroline, et al.
Published: (2012)

The composition of the gut microbiota shapes the colon mucus barrier
by: Jakobsson, Hedvig E, et al.
Published: (2015)

Phase I Trial of a Lactobacillus crispatus Vaginal Suppository for Prevention of Recurrent Urinary Tract Infection in Women
by: Czaja, Christopher A., et al.
Published: (2007)

Draft Genome Sequence of Lactobacillus crispatus EM-LC1, an Isolate with Antimicrobial Activity Cultured from an Elderly Subject
by: Power, Susan E., et al.
Published: (2013)

Interactions between Lactobacillus crispatus and Bacterial Vaginosis (BV)-Associated Bacterial Species in Initial Attachment and Biofilm Formation
by: Machado, António, et al.
Published: (2013)

Draft Genome Sequence of Lactobacillus crispatus C25 Isolated from Chicken Cecum
by: Rezvani, Morvarid, et al.
Published: (2016)

Comparative genomics of Lactobacillus crispatus suggests novel mechanisms for the competitive exclusion of Gardnerella vaginalis
by: Ojala, Teija, et al.
Published: (2014)

Draft Genome Sequence of Lactobacillus crispatus JCM5810, Which Can Reduce Campylobacter jejuni Colonization in Chicken Intestine
by: Wooten, Jessica, et al.
Published: (2016)

The Effect of Lactobacillus crispatus and Lactobacillus rhamnosusCulture Supernatants on Expression of Autophagy Genes and HPV E6 and E7 Oncogenes in The HeLa Cell Line
by: Motevaseli, Elahe, et al.
Published: (2016)

Mucoadhesive Nanoparticles May Disrupt the Protective Human Mucus Barrier by Altering Its Microstructure
by: Wang, Ying-Ying, et al.
Published: (2011)

Vaginal pH and Microbicidal Lactic Acid When Lactobacilli Dominate the Microbiota
by: O’Hanlon, Deirdre E., et al.
Published: (2013)

The Interaction of the Gut Microbiota with the Mucus Barrier in Health and Disease in Human
by: Anthony P. Corfield
Published: (2018-08-01)

Characterization of shed medicinal leech mucus reveals a diverse microbiota
by: Ott, Brittany M., et al.
Published: (2015)

Lactobacillus crispatus L1: high cell density cultivation and exopolysaccharide structure characterization to highlight potentially beneficial effects against vaginal pathogens
by: Donnarumma, Giovanna, et al.
Published: (2014)

The significance of Lactobacillus crispatus and L. vaginalis for vaginal health and the negative effect of recent sex: a cross-sectional descriptive study across groups of African women
by: Jespers, Vicky, et al.
Published: (2015)

Unraveling the Dynamics of the Human Vaginal Microbiome
by: Nunn, Kenetta L., et al.
Published: (2016)

Report of surgical correction of a cervicovaginal agenesis case: cervicovaginal reconstruction with pudendal thigh flaps
by: Abali, Remzi, et al.
Published: (2013)

Characterizing human lung tissue microbiota and its relationship to epidemiological and clinical features
by: Yu, Guoqin, et al.
Published: (2016)

Increased Vascularity in Cervicovaginal Mucosa with Schistosoma haematobium Infection
by: Jourdan, Peter Mark, et al.
Published: (2011)

Lymphoma of the cervix: A diagnostic pitfall on cervicovaginal smear
by: Calli, Aylin Orgen, et al.
Published: (2012)

Serendipitously identified Strongyloides stercoralis in a cervicovaginal smear
by: Mayekar, Vinita, et al.
Published: (2013)

Potential role of cervicovaginal extracellular particles in diagnosis of endometriosis
by: Muth, Dillon C., et al.
Published: (2015)

The Contribution of Cervicovaginal Infections to the Immunomodulatory Effects of Hormonal Contraception
by: Fichorova, Raina N., et al.
Published: (2015)

Characterisation of the vaginal Lactobacillus microbiota associated with preterm delivery
by: Petricevic, Ljubomir, et al.
Published: (2014)

Toward the modeling of mucus draining from human lung: role of airways deformation on air-mucus interaction
by: Mauroy, Benjamin, et al.
Published: (2015)

Rearing Room Affects the Non-dominant Chicken Cecum Microbiota, While Diet Affects the Dominant Microbiota
by: Ludvigsen, Jane, et al.
Published: (2016)