Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection

Cerebral malaria (CM) is a major contributor to malaria deaths, but its pathophysiology is not well understood. While sequestration of parasitized erythrocytes is thought to be critical, the roles of inflammation and coagulation are controversial. In a large series of Malawian children hospitalized...

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Bibliographic Details
Main Authors: Hochman, Sarah E., Madaline, Theresa F., Wassmer, Samuel C., Mbale, Emmie, Choi, Namjong, Seydel, Karl B., Whitten, Richard O., Varughese, Julie, Grau, Georges E. R., Kamiza, Steve, Molyneux, Malcolm E., Taylor, Terrie E., Lee, Sunhee, Milner, Danny A., Kim, Kami
Format: Online
Language:English
Published: American Society of Microbiology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611030/