Comparative Analysis of Methods to Induce Myocardial Infarction in a Closed-Chest Rabbit Model

Objective. To develop a rabbit model of closed-chest catheter-induced myocardial infarction. Background. Limitations of rodent and large animal models justify the search for clinically relevant alternatives. Methods. Microcatheterization of the heart was performed in 47 anesthetized 3-4 kg New Zeal...

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Bibliographic Details
Main Authors: Isorni, Marc-Antoine, Casanova, Amaury, Piquet, Julie, Bellamy, Valérie, Pignon, Charly, Puymirat, Etienne, Menasche, Philippe
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609376/