Suspected Anaphylactic Reaction Prior to Induction of Anesthesia

Although uncommon, anaphylactic reactions during surgery are very dangerous and can result in serious morbidity. Various anesthetics can trigger anaphylactic reactions, and incidents with cephalosporin antibiotics are on the rise. In the case presented, an 84-year-old woman scheduled for calcaneus f...

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Bibliographic Details
Main Authors: Lee, Kwang Ho, Lim, Hyun Kyo, Park, Ji Hyoung, Do, Hye Jin, Jeon, Yeong Gwan
Format: Online
Language:English
Published: Yonsei University Wonju College of Medicine 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608229/
Description
Summary:Although uncommon, anaphylactic reactions during surgery are very dangerous and can result in serious morbidity. Various anesthetics can trigger anaphylactic reactions, and incidents with cephalosporin antibiotics are on the rise. In the case presented, an 84-year-old woman scheduled for calcaneus fracture surgery, was injected with cefbuperazone as a prophylactic antibiotic. On the way to the operating room, before induction of anesthesia, the patient lost consciousness and showed signs of hypoxemia, and anaphylactic reaction, which included hypotension, bronchospasm, and rash. Five hours after immediate intubation and fluid resuscitation, the patient was extubated and transferred to the general ward. Eight weeks later, the skin prick test confirmed a positive reaction to cefbuperazone.