Antigenically Modified Human Pluripotent Stem Cells Generate Antigen-Presenting Dendritic Cells

Human pluripotent stem cells (hPSCs) provide a promising platform to produce dendritic cell (DC) vaccine. To streamline the production process, we investigated a unique antigen-loading strategy that suits this novel platform. Specifically, we stably modified hPSCs using tumour antigen genes in the f...

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Bibliographic Details
Main Authors: Zeng, Jieming, Wu, Chunxiao, Wang, Shu
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608011/