Total Synthesis of Lignan Lactone (–)-Hinokinin

Total Synthesis of Lignan Lactone (–)-Hinokinin

This research paper is aimed at studying the total synthesis of pharmacologically active lignan (–)-hinokinin. The synthesis features a three-step cascade reaction involving highly stereoselective Michael addition, anion-oxidative hydroxylation, and oxygen anion cyclization to construct the pivotal...

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Main Authors: Zhou, Qi-Long, Wang, Hui-Jing, Tang, Pei, Song, Hao, Qin, Yong
Format: Online
Language:English
Published: Springer Berlin Heidelberg 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607678/
id pubmed-4607678
recordtype oai_dc
spelling pubmed-46076782015-10-20 Total Synthesis of Lignan Lactone (–)-Hinokinin Zhou, Qi-Long Wang, Hui-Jing Tang, Pei Song, Hao Qin, Yong Original Article This research paper is aimed at studying the total synthesis of pharmacologically active lignan (–)-hinokinin. The synthesis features a three-step cascade reaction involving highly stereoselective Michael addition, anion-oxidative hydroxylation, and oxygen anion cyclization to construct the pivotal butyrolactonimidate intermediate. Springer Berlin Heidelberg 2015-10-12 /pmc/articles/PMC4607678/ /pubmed/26458924 http://dx.doi.org/10.1007/s13659-015-0073-3 Text en © The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Zhou, Qi-Long
Wang, Hui-Jing
Tang, Pei
Song, Hao
Qin, Yong
spellingShingle Zhou, Qi-Long
Wang, Hui-Jing
Tang, Pei
Song, Hao
Qin, Yong
Total Synthesis of Lignan Lactone (–)-Hinokinin
author_facet Zhou, Qi-Long
Wang, Hui-Jing
Tang, Pei
Song, Hao
Qin, Yong
author_sort Zhou, Qi-Long
title Total Synthesis of Lignan Lactone (–)-Hinokinin
title_short Total Synthesis of Lignan Lactone (–)-Hinokinin
title_full Total Synthesis of Lignan Lactone (–)-Hinokinin
title_fullStr Total Synthesis of Lignan Lactone (–)-Hinokinin
title_full_unstemmed Total Synthesis of Lignan Lactone (–)-Hinokinin
title_sort total synthesis of lignan lactone (–)-hinokinin
description This research paper is aimed at studying the total synthesis of pharmacologically active lignan (–)-hinokinin. The synthesis features a three-step cascade reaction involving highly stereoselective Michael addition, anion-oxidative hydroxylation, and oxygen anion cyclization to construct the pivotal butyrolactonimidate intermediate.
publisher Springer Berlin Heidelberg
publishDate 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607678/
_version_ 1613488843011391488

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