Bacteriophage strain typing by rapid single molecule analysis

Rapid characterization of unknown biological samples is under the focus of many current studies. Here we report a method for screening of biological samples by optical mapping of their DNA. We use a novel, one-step chemo-enzymatic reaction to covalently bind fluorophores to DNA at the four-base reco...

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Bibliographic Details
Main Authors: Grunwald, Assaf, Dahan, Moran, Giesbertz, Anna, Nilsson, Adam, Nyberg, Lena K., Weinhold, Elmar, Ambjörnsson, Tobias, Westerlund, Fredrik, Ebenstein, Yuval
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605287/