MiRNA-621 sensitizes breast cancer to chemotherapy by suppressing FBXO11 and enhancing p53 activity

MicroRNAs (miRNAs) have been demonstrated to have critical roles in regulating cancer cell proliferation, survival and sensitivity to chemotherapy. The potential application of using miRNAs to predict therapeutic response to cancer treatment holds high promise, but miRNAs with predictive value remai...

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Bibliographic Details
Main Authors: Xue, J, Chi, Y, Chen, Y, Huang, S, Ye, X, Niu, J, Wang, W, Pfeffer, L M, Shao, Z-m, Wu, Z-H, Wu, J
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603999/