The function and dynamics of the apical scaffolding protein E3KARP are regulated by cell-cycle phosphorylation

The apical scaffolding protein E3KARP, a paralogue of EBP50, is regulated by Ser-303 cell-cycle phosphorylation. This phosphorylation enhances its exchange rate in vivo and reduces its apical localization and function. The dynamics of EBP50 and E3KARP are regulated by sites in their tails, which are...

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Bibliographic Details
Main Authors: Sauvanet, Cécile, Garbett, Damien, Bretscher, Anthony
Format: Online
Language:English
Published: The American Society for Cell Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603932/