From Infancy to Adolescence: Fifteen Years of Continuous Treatment With Hydroxyurea in Sickle Cell Anemia

Despite documented laboratory and clinical benefits of hydroxyurea for children with sickle cell anemia (SCA), the drug's long-term safety and efficacy remains poorly defined. The HUSOFT trial and extension study examined feasibility, toxicity, and hematological efficacy of hydroxyurea in infan...

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Bibliographic Details
Main Authors: Hankins, Jane S., Aygun, Banu, Nottage, Kerri, Thornburg, Courtney, Smeltzer, Matthew P., Ware, Russell E., Wang, Winfred C.
Format: Online
Language:English
Published: Wolters Kluwer Health 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603125/