Activation of Vago by interferon regulatory factor (IRF) suggests an interferon system-like antiviral mechanism in shrimp

There is a debate on whether invertebrates possess an antiviral immunity similar to the interferon (IFN) system of vertebrates. The Vago gene from arthropods encodes a viral-activated secreted peptide that restricts virus infection through activating the JAK-STAT pathway and is considered to be a cy...

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Bibliographic Details
Main Authors: Li, Chaozheng, Li, Haoyang, Chen, Yixiao, Chen, Yonggui, Wang, Sheng, Weng, Shao-Ping, Xu, Xiaopeng, He, Jianguo
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602278/