Electroacupuncture Pretreatment Attenuates Cerebral Ischemic Injury via Notch Pathway-Mediated Up-Regulation of Hypoxia Inducible Factor-1α in Rats

We have reported electroacupuncture (EA) pretreatment induced the tolerance against focal cerebral ischemia through activation of canonical Notch pathway. However, the underlying mechanisms have not been fully understood. Evidences suggest that up-regulation of hypoxia inducible factor-1α (HIF-1α)...

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Bibliographic Details
Main Authors: Zhao, Yu, Deng, Bin, Li, Yichong, Zhou, Lihua, Yang, Lei, Gou, Xingchun, Wang, Qiang, Chen, Guozhong, Xu, Hao, Xu, Lixian
Format: Online
Language:English
Published: Springer US 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602051/