CNF1 Enhances Brain Energy Content and Counteracts Spontaneous Epileptiform Phenomena in Aged DBA/2J Mice

Epilepsy, one of the most common conditions affecting the brain, is characterized by neuroplasticity and brain cell energy defects. In this work, we demonstrate the ability of the Escherichia coli protein toxin cytotoxic necrotizing factor 1 (CNF1) to counteract epileptiform phenomena in inbred DBA/...

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Bibliographic Details
Main Authors: Travaglione, Sara, Ballan, Giulia, Fortuna, Andrea, Ferri, Alberto, Guidotti, Marco, Campana, Gabriele, Fiorentini, Carla, Loizzo, Stefano
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601759/