Deep venous thrombosis in a patient undergoing In-vitro fertilization with oocyte donation

Deep venous thrombosis in a patient undergoing In-vitro fertilization with oocyte donation

Deep venous thrombosis (DVT) has been reported extensively following ovarian hyperstimulation syndrome during in-vitro fertilization (IVF). Pregnancy per se increases the risk of DVT due to a hypercoagulable state. The long-term use of hormone replacement therapy (HRT) is another critical factor ass...

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Main Authors: Mahajan, Nalini, Naidu, Padmaja, Gupta, Shalu, Rani, Kumkum
Format: Online
Language:English
Published: Medknow Publications & Pvt Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601180/
id pubmed-4601180
recordtype oai_dc
spelling pubmed-46011802015-11-04 Deep venous thrombosis in a patient undergoing In-vitro fertilization with oocyte donation Mahajan, Nalini Naidu, Padmaja Gupta, Shalu Rani, Kumkum Case Report Deep venous thrombosis (DVT) has been reported extensively following ovarian hyperstimulation syndrome during in-vitro fertilization (IVF). Pregnancy per se increases the risk of DVT due to a hypercoagulable state. The long-term use of hormone replacement therapy (HRT) is another critical factor associated with DVT in women. However, an association between the short-term use of HRT in oocyte donation (OD) cycles and DVT has not yet been reported. We present a case of 43-year-old woman who developed DVT after IVF-OD. DVT was diagnosed at 7 weeks of pregnancy and was managed with low-molecular-weight heparin. We suggest that even a short-term use of HRT should be considered a risk factor for DVT especially in the presence of additional risk factors such as obesity. The patient had an uneventful recovery and delivered three healthy though preterm babies. Medknow Publications & Pvt Ltd 2015 /pmc/articles/PMC4601180/ /pubmed/26538864 http://dx.doi.org/10.4103/0974-1208.165150 Text en Copyright: © Journal of Human Reproductive Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Mahajan, Nalini
Naidu, Padmaja
Gupta, Shalu
Rani, Kumkum
spellingShingle Mahajan, Nalini
Naidu, Padmaja
Gupta, Shalu
Rani, Kumkum
Deep venous thrombosis in a patient undergoing In-vitro fertilization with oocyte donation
author_facet Mahajan, Nalini
Naidu, Padmaja
Gupta, Shalu
Rani, Kumkum
author_sort Mahajan, Nalini
title Deep venous thrombosis in a patient undergoing In-vitro fertilization with oocyte donation
title_short Deep venous thrombosis in a patient undergoing In-vitro fertilization with oocyte donation
title_full Deep venous thrombosis in a patient undergoing In-vitro fertilization with oocyte donation
title_fullStr Deep venous thrombosis in a patient undergoing In-vitro fertilization with oocyte donation
title_full_unstemmed Deep venous thrombosis in a patient undergoing In-vitro fertilization with oocyte donation
title_sort deep venous thrombosis in a patient undergoing in-vitro fertilization with oocyte donation
description Deep venous thrombosis (DVT) has been reported extensively following ovarian hyperstimulation syndrome during in-vitro fertilization (IVF). Pregnancy per se increases the risk of DVT due to a hypercoagulable state. The long-term use of hormone replacement therapy (HRT) is another critical factor associated with DVT in women. However, an association between the short-term use of HRT in oocyte donation (OD) cycles and DVT has not yet been reported. We present a case of 43-year-old woman who developed DVT after IVF-OD. DVT was diagnosed at 7 weeks of pregnancy and was managed with low-molecular-weight heparin. We suggest that even a short-term use of HRT should be considered a risk factor for DVT especially in the presence of additional risk factors such as obesity. The patient had an uneventful recovery and delivered three healthy though preterm babies.
publisher Medknow Publications & Pvt Ltd
publishDate 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601180/
_version_ 1613486422762717184

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