miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program
Macrophages play a pivotal role in tissue fibrogenesis, which underlies the pathogenesis of many end-stage chronic inflammatory diseases. MicroRNAs are key regulators of immune cell functions, but their roles in macrophage's fibrogenesis have not been characterized. Here we show that IL-4 and I...
Main Authors: | , , , , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Pub. Group
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600756/ |