Breast Cancer Arising Adjacent to an Involuting Fibroadenoma: Serial Changes in Radiologic Features

Fibroadenoma is a common benign breast lesion and its malignant transformation is rare. There have been several case reports and studies that retrospectively reviewed breast cancers that arose within fibroadenomas; however, none of these studies reported serial changes in radiologic features of the...

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Main Authors:	Park, Chae Jung, Kim, Eun-Kyung, Woo, Ha Young, Moon, Hee Jung, Yoon, Jung Hyun, Kim, Min Jung
Format:	Online
Language:	English
Published:	Korean Breast Cancer Society 2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600695/

id	pubmed-4600695
recordtype	oai_dc
spelling	pubmed-46006952015-10-15 Breast Cancer Arising Adjacent to an Involuting Fibroadenoma: Serial Changes in Radiologic Features Park, Chae Jung Kim, Eun-Kyung Woo, Ha Young Moon, Hee Jung Yoon, Jung Hyun Kim, Min Jung Case Report Fibroadenoma is a common benign breast lesion and its malignant transformation is rare. There have been several case reports and studies that retrospectively reviewed breast cancers that arose within fibroadenomas; however, none of these studies reported serial changes in radiologic features of the cancer, including findings from mammography and ultrasound (US). We report a case of breast cancer arising adjacent to an involuting fibro adenoma in a 39-year-old woman who was undergoing serial follow-up after her fibroadenoma was diagnosed. Seven years after her diagnosis, the lesion showed evidence of coarse calcifications, a typical sign of involution. Four years later, US revealed a newly developed hypoechoic lesion with irregular margins and peripherally located calcifications adjacent to the fibroadenoma. A core biopsy was performed, and histopathological examination resulted in a diagnosis of invasive ductal carcinoma. When new suspicious features are observed in a fibroadenoma, radiologists should raise the concern for breast cancer and proceed with diagnosis and treatment accordingly. Korean Breast Cancer Society 2015-09 2015-09-24 /pmc/articles/PMC4600695/ /pubmed/26472981 http://dx.doi.org/10.4048/jbc.2015.18.3.291 Text en © 2015 Korean Breast Cancer Society. All rights reserved. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Park, Chae Jung Kim, Eun-Kyung Woo, Ha Young Moon, Hee Jung Yoon, Jung Hyun Kim, Min Jung
spellingShingle	Park, Chae Jung Kim, Eun-Kyung Woo, Ha Young Moon, Hee Jung Yoon, Jung Hyun Kim, Min Jung Breast Cancer Arising Adjacent to an Involuting Fibroadenoma: Serial Changes in Radiologic Features
author_facet	Park, Chae Jung Kim, Eun-Kyung Woo, Ha Young Moon, Hee Jung Yoon, Jung Hyun Kim, Min Jung
author_sort	Park, Chae Jung
title	Breast Cancer Arising Adjacent to an Involuting Fibroadenoma: Serial Changes in Radiologic Features
title_short	Breast Cancer Arising Adjacent to an Involuting Fibroadenoma: Serial Changes in Radiologic Features
title_full	Breast Cancer Arising Adjacent to an Involuting Fibroadenoma: Serial Changes in Radiologic Features
title_fullStr	Breast Cancer Arising Adjacent to an Involuting Fibroadenoma: Serial Changes in Radiologic Features
title_full_unstemmed	Breast Cancer Arising Adjacent to an Involuting Fibroadenoma: Serial Changes in Radiologic Features
title_sort	breast cancer arising adjacent to an involuting fibroadenoma: serial changes in radiologic features
description	Fibroadenoma is a common benign breast lesion and its malignant transformation is rare. There have been several case reports and studies that retrospectively reviewed breast cancers that arose within fibroadenomas; however, none of these studies reported serial changes in radiologic features of the cancer, including findings from mammography and ultrasound (US). We report a case of breast cancer arising adjacent to an involuting fibro adenoma in a 39-year-old woman who was undergoing serial follow-up after her fibroadenoma was diagnosed. Seven years after her diagnosis, the lesion showed evidence of coarse calcifications, a typical sign of involution. Four years later, US revealed a newly developed hypoechoic lesion with irregular margins and peripherally located calcifications adjacent to the fibroadenoma. A core biopsy was performed, and histopathological examination resulted in a diagnosis of invasive ductal carcinoma. When new suspicious features are observed in a fibroadenoma, radiologists should raise the concern for breast cancer and proceed with diagnosis and treatment accordingly.
publisher	Korean Breast Cancer Society
publishDate	2015
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600695/
_version_	1613486250953539584

Breast Cancer Arising Adjacent to an Involuting Fibroadenoma: Serial Changes in Radiologic Features

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