Forebrain-Specific Loss of BMPRII in Mice Reduces Anxiety and Increases Object Exploration

Forebrain-Specific Loss of BMPRII in Mice Reduces Anxiety and Increases Object Exploration

To investigate the role of Bone Morphogenic Protein Receptor Type II (BMPRII) in learning, memory, and exploratory behavior in mice, a tissue-specific knockout of BMPRII in the post-natal hippocampus and forebrain was generated. We found that BMPRII mutant mice had normal spatial learning and memory...

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Bibliographic Details
Main Authors: McBrayer, Zofeyah L., Dimova, Jiva, Pisansky, Marc T., Sun, Mu, Beppu, Hideyuki, Gewirtz, Jonathan C., O’Connor, Michael B.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596878/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596878/

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