Modelling Blood Flow and Metabolism in the Preclinical Neonatal Brain during and Following Hypoxic-Ischaemia

Hypoxia-ischaemia (HI) is a major cause of neonatal brain injury, often leading to long-term damage or death. In order to improve understanding and test new treatments, piglets are used as preclinical models for human neonates. We have extended an earlier computational model of piglet cerebral physi...

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Bibliographic Details
Main Authors: Caldwell, Matthew, Moroz, Tracy, Hapuarachchi, Tharindi, Bainbridge, Alan, Robertson, Nicola J., Cooper, Chris E., Tachtsidis, Ilias
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596480/