A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

Existing knowledge of genetic variants affecting risk of coronary artery disease (CAD) is largely based on genome-wide association studies (GWAS) analysis of common SNPs. Leveraging phased haplotypes from the 1000 Genomes Project, we report a GWAS meta-analysis of 185 thousand CAD cases and controls...

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Main Authors: Nikpay, Majid, Goel, Anuj, Won, Hong-Hee, Hall, Leanne M, Willenborg, Christina, Kanoni, Stavroula, Saleheen, Danish, Kyriakou, Theodosios, Nelson, Christopher P, Hopewell, Jemma C, Webb, Thomas R, Zeng, Lingyao, Dehghan, Abbas, Alver, Maris, Armasu, Sebastian M, Auro, Kirsi, Bjonnes, Andrew, Chasman, Daniel I, Chen, Shufeng, Ford, Ian, Franceschini, Nora, Gieger, Christian, Grace, Christopher, Gustafsson, Stefan, Huang, Jie, Hwang, Shih-Jen, Kim, Yun Kyoung, Kleber, Marcus E, Lau, King Wai, Lu, Xiangfeng, Lu, Yingchang, Lyytikäinen, Leo-Pekka, Mihailov, Evelin, Morrison, Alanna C, Pervjakova, Natalia, Qu, Liming, Rose, Lynda M, Salfati, Elias, Saxena, Richa, Scholz, Markus, Smith, Albert V, Tikkanen, Emmi, Uitterlinden, Andre, Yang, Xueli, Zhang, Weihua, Zhao, Wei, de Andrade, Mariza, de Vries, Paul S, van Zuydam, Natalie R, Anand, Sonia S, Bertram, Lars, Beutner, Frank, Dedoussis, George, Frossard, Philippe, Gauguier, Dominique, Goodall, Alison H, Gottesman, Omri, Haber, Marc, Han, Bok-Ghee, Huang, Jianfeng, Jalilzadeh, Shapour, Kessler, Thorsten, König, Inke R, Lannfelt, Lars, Lieb, Wolfgang, Lind, Lars, Lindgren, Cecilia M, Lokki, Marja-Liisa, Magnusson, Patrik K, Mallick, Nadeem H, Mehra, Narinder, Meitinger, Thomas, Memon, Fazal-ur-Rehman, Morris, Andrew P, Nieminen, Markku S, Pedersen, Nancy L, Peters, Annette, Rallidis, Loukianos S, Rasheed, Asif, Samuel, Maria, Shah, Svati H, Sinisalo, Juha, Stirrups, Kathleen E, Trompet, Stella, Wang, Laiyuan, Zaman, Khan S, Ardissino, Diego, Boerwinkle, Eric, Borecki, Ingrid B, Bottinger, Erwin P, Buring, Julie E, Chambers, John C, Collins, Rory, Cupples, L Adrienne, Danesh, John, Demuth, Ilja, Elosua, Roberto, Epstein, Stephen E, Esko, Tõnu, Feitosa, Mary F, Franco, Oscar H, Franzosi, Maria Grazia, Granger, Christopher B, Gu, Dongfeng, Gudnason, Vilmundur, Hall, Alistair S, Hamsten, Anders, Harris, Tamara B, Hazen, Stanley L, Hengstenberg, Christian, Hofman, Albert, Ingelsson, Erik, Iribarren, Carlos, Jukema, J Wouter, Karhunen, Pekka J, Kim, Bong-Jo, Kooner, Jaspal S, Kullo, Iftikhar J, Lehtimäki, Terho, Loos, Ruth J F, Melander, Olle, Metspalu, Andres, März, Winfried, Palmer, Colin N, Perola, Markus, Quertermous, Thomas, Rader, Daniel J, Ridker, Paul M, Ripatti, Samuli, Roberts, Robert, Salomaa, Veikko, Sanghera, Dharambir K, Schwartz, Stephen M, Seedorf, Udo, Stewart, Alexandre F, Stott, David J, Thiery, Joachim, Zalloua, Pierre A, O’Donnell, Christopher J, Reilly, Muredach P, Assimes, Themistocles L, Thompson, John R, Erdmann, Jeanette, Clarke, Robert, Watkins, Hugh, Kathiresan, Sekar, McPherson, Ruth, Deloukas, Panos, Schunkert, Heribert, Samani, Nilesh J, Farrall, Martin
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589895/