Epigenetic signatures of internal migration in Italy

Background: Observational studies have suggested that the risks of non-communicable diseases in voluntary migrants become similar to those in the host population after one or more generations, supporting the hypothesis that these diseases have a predominantly environmental (rather than inherited) or...

Full description

Bibliographic Details
Main Authors: Campanella, Gianluca, Polidoro, Silvia, Di Gaetano, Cornelia, Fiorito, Giovanni, Guarrera, Simonetta, Krogh, Vittorio, Palli, Domenico, Panico, Salvatore, Sacerdote, Carlotta, Tumino, Rosario, Elliott, Paul, Matullo, Giuseppe, Chadeau-Hyam, Marc, Vineis, Paolo
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588856/
Description
Summary:Background: Observational studies have suggested that the risks of non-communicable diseases in voluntary migrants become similar to those in the host population after one or more generations, supporting the hypothesis that these diseases have a predominantly environmental (rather than inherited) origin. However, no study has been conducted thus far to identify alterations at the molecular level that might mediate these changes in disease risk after migration.